About

Our 8th Annual meeting of FTD researchers across the UK will be on 21st September 2018 in Manchester.

FTDUK is co-ordinated by Dr Jonathan Rohrer (University College London), Dr James Rowe (University of Cambridge) and Prof Stuart Pickering-Brown (University of Manchester).

2018 Programme

Friday 21st September 2018
9.30amRegistration
10.00amWelcome to the meeting and introductionProfessor Stuart Pickering-Brown, Dr Jonathan Rohrer & Professor James Rowe
10.10amThe MLSEPeter Garrard (St George’s Hospital London)
10.30amFunctional Networks in Genetic FTD – Susceptibility and ResilienceTim Rittman (University of Cambridge)
10.50amDisease modelling approaches to FTDAlexandra Young (UCL)
11.10amCoffee break
11.40amThere’s something wrong with my MAM; ER-mitochondria signaling and neurodegenerative diseasesChris Miller (King's College London)
12.00pmC9orf72 FTD/ALS: mechanisms and therapeuticsAdrian Isaacs (UCL)
12.20pmGene therapy approaches to ALSPam Shaw (Sheffield)
12.40pmLunch
1.40pmNovel therapies for GRN-related FTDRobert Paul (Alector)
2.00pmNovel cell-based therapies for FTDJohan Lundkvist (Alzecure)
2.20pmCoffee break
2.50pmImproving the diagnostic pathway for patients with FTDPanel discussion
3.30pmBasic Science Prize for Early Career UK FTD Researcher
3.40pmClinical Science Prize for Early Career UK FTD Researcher
3.50pmUpdate on UK dementia initiatives
4.00pmFinish

2017 Programme

Friday 29th September 2017
9.30amRegistration
10.00amWelcome to the meeting and introductionProfessor Stuart Pickering-Brown, Dr Jonathan Rohrer & Professor James Rowe
10.10amNeuropsychological profiles in FTD and ALS-FTDJennifer Saxon (University of Manchester)
10.30amNovel PET ligands for imaging neurodegenerationIlan Rabiner (Imanova)
10.50amStaging systems in ALS - incorporating FTD and cognitive impairmentAmmar Al-Chalabi (King's College London)
11.10amCoffee break
11.40amNew models of tauopathyDiane Hanger (King's College London)
12.00pmModelling FTD with patient-derived iPSC-neuronsSelina Wray (UCL)
12.20pmInvestigating protein degradation deficits in FTDGemma Lace-Costigan (Salford University)
12.40pmLunch
1.40pmStereopure oligonucleotides as a therapeutic approach to rare neurological diseasesMichael Panzara (WAVE Life Sciences)
2.00pmThe age of tau therapy – from shadow to sunlightNorbert Žilka (Axon)
2.20pmCoffee break
2.50pmDeveloping standards of care in the diagnosis and management of FTDPanel discussion
3.30pmBasic Science Prize for Early Career UK FTD Researcher
3.40pmClinical Science Prize for Early Career UK FTD Researcher
3.50pmUpdate on UK dementia initiatives, including IFGC update, and summary of day
4.00pmFinish

2016 Programme

Friday 4th November 2016
9.30amRegistration
10.00amWelcome to the meeting and introductionProfessor Stuart Pickering-Brown, Dr Jonathan Rohrer & Professor James Rowe
10.10amTau PET imaging in PSPProfessor James Rowe (University of Cambridge)
10.30amImaging of subcortical structures and their connections in FTDDr Martina Bocchetta (UCL)
10.50amClinical, imaging and path features of TBK1 mutations in FTD and ALSDr Jonathan Rohrer (UCL)
11.10amCoffee break
11.40amAntisense and sense RNA foci derived from repeat expansions of C9orf72 have similar interactions but distinct expression patternsDr Jonathan Cooper-Knock (University of Sheffield)
12.00pmModelling C9orf72 dipeptide repeats: size mattersDr Sarah Ryan (University of Manchester)
12.20pmGenetic modifiers of CHMP2BDr Sean Sweeny (University of York)
12.40pmLunch
1.40pmDevelopment of the tau directed monoclonal antibody BMS-986168 for the treatment of PSPIrfan Qureshi (BMS)
2.00pmO-GlcNAcase inhibition as potential treatment for tauopathiesDirk Beher (Asceneuron)
2.20pmCoffee break
2.50pmAn update on ALS research in the last yearProfessor Chris Shaw (King’s College London)
3.10pmThe new PSP criteria and an update on the PROSPECT studyProfessor Huw Morris (UCL)
3.30pmAn update on UK dementia initiatives and the role of FTD, PSP, CBS and ALS in these initiativesProfessor Stuart Pickering-Brown, Dr Jonathan Rohrer & Professor James Rowe
3.45pmFinish

2015 Programme

5th annual FTDUK meeting

Friday 11th September 2015
9.30amRegistration
10.00amWelcome to the meeting and introductionProfessor Stuart Pickering-Brown, Dr Jonathan Rohrer & Dr James Rowe
10.10amEpidemiology of FTD - the PiPPIN studyDr Ian Coyle-Gilchrist (University of Cambridge)
10.30amCSF and serum biomarkers in FTDProfessor Henrik Zetterberg (UCL)
10.50amSerum markers in MND and their relevance to FTDDr Martin Turner (University of Oxford)
11.10amCoffee break
11.40amCurrent therapeutic trials in FTDDr Catherine Mummery (UCL)
12.00pmNovel tau therapeuticsRoger Lane (Isis Pharmaceuticals)
12.20pmInflammatory PET imagingDr Alex Gerhard (University of Manchester)
12.40pmLunch
1.40pmThe role of TDP-43 in neurodegenerative diseaseDr Tammaryn Lashley (UCL)
2.00pmNovel MND genes and their relevance to FTDProfessor Kevin Talbot (University of Oxford)
2.20pmCoffee break
2.50pmUpdates in UK FTD researchProfessor Stuart Pickering-Brown, Dr Jonathan Rohrer & Dr James Rowe
3.15pmFinish

2014 Programme

4th annual FTDUK meeting

Friday 12th September 2014
Basement Lecture Theatre, 33 Queen Square, London, WC1N 3BG
9.30amRegistration
10.00amWelcome to the meeting and introductionProfessor Stuart Pickering-Brown, Dr Jonathan Rohrer & Dr James Rowe
10.10amNew findings in the genetics of C9orf72Professor Stuart Pickering-Brown (University of Manchester)
10.30amMechanisms of toxicity in C9FTD/ALSDr Sarah Mizielinska (UCL)
10.50amTau aggregation and neurodegenerationProfessor Michel Goedert (University of Cambridge)
11.10amCoffee break
11.40amWhere are we with tau PET imaging of FTD?Dr Franklin Aigbirhio (University of Cambridge)
12.00pmMechanisms of tau propagationSuchira Bose (Lilly)
12.20pmThe clinical stage HDAC inhibitor FRM-0334 induces progranulin in a variety of pre-clinical model systemsHolger Patzke (Forum Pharmaceuticals)
12.40pmLunch
2.00pmPhysiological phenotyping of frontotemporal lobar degenerationsDr Jason Warren (UCL)
2.20pmWhat rating scales should we be using in clinical trials of FTD?Professor John Hodges (Neuroscience Research Australia) & Dr Eneida Mioshi (University of Cambridge)
2.40pmWhat is the role of episodic memory in FTD?Dr Michael Hornberger (University of Cambridge)
3.00pmCoffee break
3.30pmUpdates on national and international dementia initiatives in relation to FTD research and summary of the dayProfessor Stuart Pickering-Brown, Dr Jonathan Rohrer & Dr James Rowe